Master Class: cancer and longevity 2019

“It is already possible to live to be well over 120 years (…) In my own laboratory at UCLA Medical Center, we have extended the maximum life span of fish by 300 percent.” Maximum Life Span”, NY: W. W. Norton, 1983  by Roy L. Walford, M.D.

Certification Program to become an Optimal Longevity & Holistic Oncology Citizen Coach

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The objective of this Master Class is to train coachees so that they can become competent Optimal Longevity & Holistic Cancer coaches either for themselves and-or others. It is the ACR Institute’s belief that the more skilled Holistic Coaches we have, the healthier Society will become.

The Originality of this Training

This Master class tackles cancer from the longevity and bio-terrain angle with the best available Science and healing practices. By addressing the tumor (s) microenvironment as well as the person’s bioterrain holistically and with Optimal Longevity medicine, the body will more often than not resolve the cancer as well as many of the other degenerative challenges the patient may be suffering from.  It is our belief and experience that there is  no need to spend hundreds of billions of dollars fighting each year cancer with cytotoxic chemo poisons,  ionic cancer producing radiation, surgery knives, synthetic targeted therapies, genetic therapies or anything else that costs a fortune and that are loaded with toxic (side) effects and stress.

Introduction to Holistic Rejuvenation Medicine

Achieving 120 years of Life-span in Good shape and Cancer-free

From Theory to Practical Tools to Reach 120 years in good shape 

 Once the coachee-student is taught the tools to better understand the fundamental mechanisms of  holistic living and slow aging, we can then delve into some clinical experience,  starting with the first physiological priority which is Holistic Cardiology. Thereafter, we analyse the Gut-Brain axis, (with a special focus on Alzheimer’s Disease and Depression) as well as the gastro-intestinal system, holistic dentistry and the body’s six detoxification pathways in association with brain health enhancement, the endocannabinoid system’s regulation, bio-physics, the immune system and a few other longevity techniques. Diet being essential, we will examine different nutritional approaches as well as aromatherapy, wine medicine, thermal therapies, microbiota diversity, holistic cancer protocols, circadian biology, restorative sleep and more. To become an effective coach, the workshopee will need to understand Methodology, Medical Law and the inner saboteur paradox (psycho-neuro-immunology). We will conclude this Training with an overview on  supplementation and different Longevity enhancement techniques that target the mitochondria, senescent cells, autophagy, hormonal imbalance, telomerase activation, circulatory tumor cells, genes, stem cells regeneration, Lab monitoring and more.

We will also give an update on the latest bio-tech and  innovative research on optimal longevity, some of which are in clinical trials.

Top: Tibetan Mountain Goji Berries, a favorite super fruit  among supercentenarian Chinese Taoists and Tibetan Buddhists. Its polysaccharides  have many benefits including by enhancing:  “… neurogenesis in the hippocampus and subventricular zone, improving learning and memory abilities” (Source)

The Certification’s Presentations are supported with Strong Science

The Certification’s content will be supported with strong published peer-reviewed evidence that will be visible either via internet posts, power point and-or video. For an introduction to the subject presented by Professor Joubert, see  video A below. For a general overview on where we are today in terms of innovative Bio-Tech Research and longevity genes, see video D from Professor Sinclair.

Certification Modality

Two hours per week, (or as negotiated) personal (one-to-one) coach-education for 26 weeks via skype or another online video network with Pr. Joubert. That’s half a year of cutting-edge education, the application of which can safely and efficiently prevent and reverse cancer as well as many other degenerative diseases while significantly extending Life.

Each session will have a Q & A. The Price is 15,000 dollars. Mid-term and Final exams are included. If  students fails, they will have another possibility to pass the exams for 250 dollars. Once passed, students will receive the Institute’s Coaching Certification that will enable them to be Holistic Cancer & Optimal Longevity Coaches. The price is relatively pricy because the value of this Master Class is without parallel in the health education, oncology and anti-aging fields. It is more cutting-edge and useful that what Ivy league Medical schools like Harvard teach and the tuition there for something comparable would be much higher. Be that as it may, once the Institute is better funded, the price will go down and for low-income holistic-health enthusiasts, scolarships and-or sliding scale based tuitions will be eventually possible.

To Read  this Master Class’ Introduction, see Chapter Two of the Optimal Longevity Book, via click.

Most of the Source links of this Master Class have been removed, as they are part of the training.


Opening Exercise

Longevity & Mind Enhancement Meditation Exercise

“And the LORD said, My spirit shall not always strive with man, for that he also is flesh: yet his days shall be one hundred and twenty years.” (Genesis 6:3: King James Version)

Researchers at the  University of California were the first to show that meditators have significantly higher telomerase activity than non-meditators.  Furthermore, the regular practice of specific types of Meditations will simultaneously signal longevity genes to activate telomerase and sharpen both intuition and focus. As a bonus, intellectual assimilation of the content of this Certification program will be enhanced. We will therefore begin and end each 2 hours training with short guided Meditation practices.

Analysis: The Magic of Meditation: From Genomic Expression to JDV Consciousness Activation (Source)


Session A: Introduction to Holistic Rejuvenation Medicine

“The field of ageing research has been completely transformed in the past decade. . . . When single genes are changed, animals that should be old stay young. In humans, these mutants would be analogous to a ninety year old who looks and feels forty-five. On this basis we begin to think of ageing as a disease that can be cured, or at least postponed. . . . The field of ageing is beginning to explode, because so many are so excited about the prospect of searching for – and finding – the causes of ageing, and maybe even the fountain of youth itself”. (Guarente and Kenyon, Nature, 2000)

For millennia, the aging process has been considered to be uncontrollable, even when the average lifespan did not surpass 40 years, which was just a little over 100 years ago. That changed with Professor Elizabeth Blackburn’s discovery of the telomerase gene. (Source) Furthermore, in the early nineties, research on C. elegans, (a tiny nematode worm) confirmed that a single gene mutation extended its life, and that another mutation blocked that extension. (Source)The idea that age could be tweaked by twiddling a few control genetic switches ignited a research and investment boom. As more geroscientists  got better motivated to attempt to break and hack the Longevity Code, new findings started to reveal key biological clocks that epigenically switched on and off longevity genes. (See Exhibit C)

In this perspective, various clinical interventions did increase the worm’s lifespan by a factor of ten and those of lab mice by a factor of two. (Source) Thereafter, telomeres of skin cells were tweaked to lengthen considerably, thanks to a new Lab procedure fine-tuned by Stanford university School of Medicine scientists, these cells were able to divide up to 40 more times more than untreated cells, which means that human somatic cells have been shown to surpass the Hayflick limit and potentially extend their lifespan 40 times more than before. “Skin cells with telomeres lengthened by the procedure were able to divide up to 40 more times than untreated cells”. (Source)

The scientific consensus thus transformed. Aging went from being a God given blessing or Satan’s curse, to an inevitable final stage (Cf  Time cover from 1958: “Growing Old Usefully”), followed by a social issue (Time, 1970: “Growing Old in America: The Unwanted Generation”) to this avoidable “je ne sais quoi” phenomenon (1996: “Forever Young”) that could defer death to 142 years for starts (Cf 2015: Time “This Baby Could Live to Be 142 Years Old”).

However, the excitement was not long lasting, if only because it was discovered not too long ago that telomerase was not the central longevity engine anti-aging experts had hoped for. The Longevity Code cook-book is far more complex for mammals and even more so for humans than for a C. Elegans worm, fly, mouse, naked mole or even the bat (who has an exceptionally long lifespan).

Hence, Pr. Joubert scientific attitude is to prefer the known fundamentals that work to at least 122 years of age while being open to and expecting the best of bio-tech longevity engineering stratagems, many of which are still in the early phases of clinical trials and concomitant marketing schemes.

As we will see, there are many dozens of ongoing drugs and supplements that are already being used in today’s anti-aging and baby-boomer communities, from telomerase activators and senescent cell removal, (senolytics) to autophagy inducers, caloric restriction mimickers, blood donor plasma transfer, nano-robots, mTOR drugs like rapamycin, gene editing, stem cell cyro-preservation, sirtuin-activating molecules, insulin-modulating drugs like  metformin and more.

Some of these products are still under investigation in different clinical trials. Many have not even been tested in terms of drug-supplement interactions. Not only it can take many years for many of these anti-aging human trials to be completed, but once on the market, many of these anti-aging products will be too expensive for the general public and many of these products are not immune from deleterious side effects. As a consequence, risks may outweigh benefits, especially for people who are relatively healthy and are just seeking to add 30 or 40 extra years to their lifespan.

Thus, waiting a few years before some of these bio-tech longevity hacks may be accessible and proven safe and effective is not cellularly or financially responsible, if only because today we have the knowledge that key holistic tools can significantly help to rejuvenate, repair and restore most metabolically impaired tissues. Furthermore, Holistic and Happiness medicine can also meaningfully help to offset and significantly delay Evolution’s programmed aging process. In effect, by addressing senescent cells with the ACR Institute’s discoveries and techniques, we can also clear ectopic endometrial cells as well as cancer cells.


 Each session is supported with multiple sources and practical tips

Sunflowwer is the Retreat's emblem

Session A: The Basics of Biogerontology

“The idea is to die young as late as possible.” (Ashley Montagu).

Biogerontology: principles and key Findings (Source)

Distinction between Accelerated and Delayed Aging (Source)

The ACR and O.L. Institutes’ central Premise on Aging and Longevity (Source)

Nobel Professors of Physiology whose recent findings have meaningfully enhanced the value of Rejuvenation Medicine (Source)

Biomarkers (Aging and Longevity) (Source)

The Epigenetic Clock (Source)

Case studies of a few Humans and Animals who have significantly outlived their peers (Source)

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Top: The French Mediterranean dancer,  Madame Jeanne Calment, a Piscean born on February 21, 1875,  is still  the  Optimal Longevity Champion, notwithstanding some evidentiary controversies. Having reached 122.5 years, according to her claims,  she “allowed” herself to die. In other words, she could have continued to live. Her age was confirmed via birth certificate and the Guiness Record scientist-investigators, in conjunction with university experts, confirmed this fact as well as many other facts that proved beyond any reasonable doubt that human beings were capable of reaching 122 years of Life without major chronic diseases and without any drugs or supplements. In this picture, she was 120.

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What are the genetic variants or determinants that account for extreme longevity in humans ? Do these variants prevail over Lifestyle and the environment ? (Source)

“Centenarians are the best example of extreme human longevity, and they represent a selected population in which the appearance of major age-related diseases, such as cancer, and cardiovascular diseases among others, has been consistently delayed or escaped. The study of the long-lived individual genetic profile has the purpose to possibly identify the genes and the allelic variations influencing extended life expectancy, hence considering them as biomarkers of age-related diseases onset and development. The present study shows no significant differences between allelic variations of ABO blood groups among a group of centenarians from Western Sicily”. (Source)

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Session B. The Biology of Aging: Understanding the Mechanisms that Spur Accelerated & Delayed Aging

“Medicine is not only a science; it is also an art. It does not consist of compounding pills and plasters; it deals with the very processes of life, which must be understood before they may be guided.” Paracelsus

What is Biological Aging & Senescence ? (Source)

Cellular and Organismal Senescence is not shared by all Living Beings (Source)

Different Theories of Biological Aging (Source)

Cancer cells & Supercentenarians: Common threads (Source)

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Top: A young infant girl who suffers from  Proregia syndrome. She is only around 2 years old, but appears much more. Also known as Hutchinson-Gilford syndrome, this disease is  genetic. It is characterized by accelerated aging that is accompanied with the age-related diseases.  The mean age at death of these patients is 12.5 years. These children die “old” before 15 or 20, at which point they look like 80 years old.

Case study A: Ultra rapid metabolic accelerating-aging (Source)

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Top: A 16 years old little girl who stopped growing at 11 months.

Case Study B: Ultra-slow Growth: Children who do not Age, genetically “frozen” in Time (Source)


Roundworms Experimentations confirm: aging and lifespan is regulated in part through the insulin/IGF-1 and mTOR pathways. (Source)

Top: the  transparent nematodeC. elegans.This roundworm is one of the most studied for neurodegeneration and longevity. Scientists have been able to significantly extend its lifespans by tweaking its genes. 

The IGF-1 & mTOR pathways (Source)

In Search for a Working Hypothesis of the Key mechanism(s) of Aging (Source)

The Major Molecular Mechanisms that best Explain the Aging Process (Source)

The Nine Central Hallmarks of Aging (Source)

1. Genomic instability.

2. Mitochondrial DNA Break-down & Dysfunction

3. Telomere Shortening and Telomerase Depletion

4. Epigenetic Alterations

5. Loss of Proteostasis

6. Deregulated Nutrient-sensing

7. Cellular Senescence

8. Stem Cell Exhaustion

9. Altered Intercellular Communication.

Summary on the First Nine Hallmarks

Complementary Hallmarks identified by the ACR & OL Institutes (Source)

Longevity Mechanisms in supercentenarian & long-lived animals (Source)

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Top: The naked mole rat who also broke the world record for longevity in its category. This fleshy rat is one of the ACR and OL Institute’s Heros as the NM Rat has demonstrated successful Longevity pathways that are relevant to the OL Institute’s Optimal Longevity Model.

Negligible senescence in the longest living rodents, the naked mole-rats & their DNA repair system (Source)

Gompertz Aging law and  Biological “Immortality” (Source)

Tentative Concluding Remarks  on Senescence and Aging mechanisms (Source)

The Workshop’s Guiding Hypothesis on a unified theory of aging (Source)

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 Clinical Practice

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Top: coronary heart disease can be easily detected with a simple ear examination anyone can do

Session C: Holistic Cardiology in a Nutshell.  

“Keep a quiet heart, Sit like a tortoise, Walk sprightly like a pigeon, Sleep like a dog”  (Longevity advise from Li Ching-Yuen. Li was a mountain herbalist & a wine enthusiast who seemingly lived to 197 years.

Extended Lifespans need Strong Hearts & Smooth Vasculature (Source) 

Erectile Dysfunction (E.D.) is a  “CVD canary in the Coal Mine” symptom that justifies an immediate rendez-vous with Cardiology Monitoring (Source)

Debunking myths & misleading claims regarding Fats (Source)

To Salt or Not to Salt ? The Evidence on Salt and CVD Diseases (Source)

Case Studies: Reversing Cardio-vascular diseases (CVDs) with Holistic Cardiology (Source)

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Session D: Detoxification, Fasting & Cleansing for Optimal Longevity

 “There were never so many able, active minds at work on the problems of disease as now, and all their discoveries are tending toward the simple truth that you can’t improve on nature.” (Thomas Edison, 1902)

The Body’s has Six Key Metabolic Detoxification Pathways that need to be activated and fined-tuned. (Source)

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Sauna, Hydrotherapy & Hot tub Therapies (Source)

Removing Glyphosate & other deleterious chemicals ASAP (Source)

Detoxing from heavy metals, molds and damaging parasites (most molds & parasites thrive on heavy metals) (Source)

Home Detox from the Sick Building Syndrome (Source)

Occupants of water-damaged buildings (WDBs) (Source)

 Fasting  Techniques for Detoxification (Source)

 On the New “fasting mimicking diet” trend being adopted by the Anti-Aging Community (Source)

Chelators and Binders (Source)

What is the best Diet, the best nutrients, the best lifestyle and the best supplements for safe and efficient detoxification (Source)

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Juicing Cleanses (Source)

 What is the best “detox” water to Drink ? (Hydration & Types of Water) (Source)

The Myth of Drinking Lots of Water (Source)

Some “Toxicant & Cellular garbage disposal” help from our Microbiota  Gluthatione-producing Friends (Source)

Case Studies A : Titanium Dioxide Nanoparticles & Other examples (Source)

Case Studies B: Arsenic, Mercury, Cadmium, DDT, Lead, Candles and More (Source)


Session E: Quality, Traditional & Moderate Wine intake extends Healthy Lifespans 

“Stop drinking only water, and use a little wine because of your stomach and your frequent illnesses.” 1 Timothy 5:23

On the issue of “Moderate” and “biologically indicated” quality wine (Source)

Does One glass of Red Wine a day contain enough Live Chemistry for Longevity Benefits ? (Source)

Why most pub-med published articles on wines are flawed (Source)

Case Studies (Source)

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Session F: Endocannabinoid System, Homeostasis & Longevity

“It’s not because we are old that we don’t play, it’s because we don’t play that we get old” (George Bernard Shaw)

Is the Body’s Endocannabinoid System essential  insofar as general homeostasis, wellbeing & Longevity are concerned ? (Source)

The Big Three C’s: Cannabinoids, Curcuminoids and Carotenoids (Source)

Case study: Cannabinoids and Cancer (Source)

Case Study: Cannabinoids and Longevity pathways (Source)

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Session G: Research, Methodology & Legal Perspectives

“The case against science is straightforward: much of the scientific literature, perhaps half, may simply be untrue. Afflicted by studies with small sample sizes, tiny effects, invalid exploratory analyses, and flagrant conflicts of interest, together with an obsession for pursuing fashionable trends of dubious importance, science has taken a turn towards darkness.” (Lancet Journal)

The Limitations of Conventional Science, Medical Schools & Clinical Practice (Source)

How to Find reliable scientific Data (Source)

Are Animal Experimentation studies reliable ? (Source)

 Medical Law: Liability, the Standard-of-Care & the Legal Protection of Alternative Medicine &  Innovative Medical Research (Source)

Case Study on Autologous Stem Cells, Cancer and the FDA (Source)

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Session H: The French & Holistic Approach to Health & Optimal Longevity

“The fixity of the milieu supposes a perfection of the organism such that the external variations are at each instant compensated for and equilibrated. Therefore, far from being indifferent to the external world, the higher animal is on the contrary constrained in a close and responsive relation with it, of such fashion that its equilibrium results from a continuous and delicate compensation established as if by the most sensitive of balances.” (Professeur Claude Bernard)

Joie de Vivre, French Cuisine & Tradition (Source)

Case Study A: French Homeopathy: Science, Wishful Thinking, Witchcraft or Fraud  ? (Source)

Case Study B: Auriculotherapy (Ear Acupuncture): French Quakery, Chinese pseudoscience or evidence-based Medicine ? (Source)

Case Study C: Acupuncture and Longevity Optimization (Source)


 Session I: Hands-On Practical Tips: Culinary Remedies, Longevity Smoothies, Essential Oils & Wine Demonstration

“Wine can be a poison, a food or a medicine depending on  the dosage” Paracelsus

Hormonal balancing

Session J: Bio-Physics, Photons, Helio-therapy & inter-cellular Communication, Electro-acupuncture & TCM

“We are still on the threshold of fully understanding the complex relationship between light and life, but we can now say emphatically, that the function of our entire metabolism is dependent on light.” Dr. Fritz Albert Popp

Bio-Physics: Generalities (Source)

Photons and Physiology (Source)

Heliotherapy (Source)

Addressing Systemic Inflammation and inter-cellular Communication (Source)

Case Study: Cell Phone Radiation & EMFs Toxicity and Calcium Ion Channels (Source)

Electro-acupuncture and Longevity (Source)

Traditional Chinese Medicine and Longevity (Source)

Acu-pressure, traditional Oriental Medicine, Yoga workshop.

Case Studies: Addressing diseases with Frequency & Electro-medicine & TCM: Brain Cancer and more (Source)


Session K: Dental Holistic Care 

“Most chronic diseases have a dental connection” Dr Huggins

How the Conventional Toxic Dentistry Model impedes Americans from reaching healthy Lifespans (Source)

Toxic Conventional Dentistry (BPA and-or Mercury based fillings, flawed root canals, cavitation issues and more) (Source)

On the Horizon: Dental stem cells (Source)

Aromatherapy: for oral cavity and body health (Source)

Case study: The link between the Oral Cavity and Chronic Diseases (Cancer, CVDs and others) (Source)


Session L: The Reversal of Alzheimer’s Disease & Depression with Holistic Savoir-Faire & Exercises

“In investigating nature you will do well to bear ever in mind that in every question there is the truth, whatever our notions may be. This seems, perhaps, a very simple consideration, yet it is strange how often it seems to be disregarded. I remember at an early period of my own life showing to a man of high reputation as a teacher some matters which I happened to have observed. And I was very much struck and grieved to find that, while all the facts lay equally clear before him, those only which squared with his previous theories seemed to affect his organs of vision.” (Lister)

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Detecting Alzheimer’s disease many years before symptomatology by looking at the Eye (Source)

 Having APOE4 gene significantly ups Alzheimer’s Risk.  Holistic Techniques can remove these Risks (Source)


Holistically inspired Movement  attenuates the deleterious effects of APOE4 & all other chronic diseases while boosting Telomeres, HGH & DHEA (Source)

 Case studies: Reversing Alzheimer’s Disease with Holistic Medicine (Source)


Depression and Holistic Medicine (Source)

 Depression and Gut Disorders (Source)

Case Study :  Depression, stress, inflammation and meditation (Source)

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Session M: The Microbiota Revolution in Medicine & how Microbiome Medicine Optimizes Longevity

“ ..aging can be modulated by genetic pathways and biochemical processes which are evolutionarily conserved” (Lopez‐Otin et al., 2013))

Microbiota Biology & Dysbiosis (Source)


Case study A: The Microbiota, Genes and Colon Cancer: Do Human eukaryotic genes cross-talk with Bacterial Genes ? (Source)

Case B: Are the Gut’s Bacteria capable of Detoxify human chemicals while favorably modulating ROS ? (Source)

Case Study C: The Gut microbiata via fecal transplants and the reversal of multiple diseases. (Source)

Should Stool testing be part of all Diagnosis Work-ups ? (Source)

Screen Shot 2018-06-02 at 3.17.15 AM Session N: Holistic Nutrition, Gastroenterology, Weight Management & Diabetes.

“He will not look upon the rivers, the streams flowing with honey and curds”. Job 20:17

What is the Best Diet for Energy Production, Memory Maintenance, Hormonal Optimization, Tissue & DNA repair, immune-enhancement and Cancer-Free Long Lifespans to 120 Years  that is also good for the Planet ?

The “Paleo-Keto-Mediterranean-Vegan-Caloric Restriction-Diet Variation” Debate (Source)

Case Study A on the Keto and Paleo Diets (Source)

An effective recipe to die crippled with an onslaught of chronic diseases (Source)

Case Study B on Reversing Diabetes Holistically (Source)

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 Happiness Medicine Institute’s Mediterranean Rejuvenation  Recommendations (Source)

Case Study A: The Joie de Vivre French Approach to Food & the Art of Slow Eating (Source)

Case Study B: The Doctrine of Signatures (Teleological Nutritional Targeting) (Source)

Case Study  C:  Soy & Health (Source)

Case Study D: Can Quality A2 Traditional-made Cheese be a Longevity and Medical Food ? (Source)

Case Study E: The French Paradox on the High Cholesterol & Low CVDs (Source)

Wine as medicine workshop

Top:  In France, Cheese is prefered raw and organic, from grass fed animals, without antibiotics and artificial hormones and combined with wine. Although A-1 cow cheese is cheaper, most of the French prefer sheep and goats cheese, if only because these cheese have healthier casein protein and lipid profile than cow cheese, hence the gusto-olfactory contentment.  As an accompaniment, polyphenol-rich wine and when available, organic fresh grapes, olives and nuts are also indicated. This custom helps with digestion, bio-availability and mineral balance.  Organic catechin-rich Green tea can also help to burn cheese’s rich saturated and unsaturated fat content while flooding the bloodstream with complementary antioxidants, blood-thinning compounds and immuno-building molecules. A2 cheese is also rich in important fats, like DHA as well as its many fat-soluble vitamines, like Vitamin A, D and the prized K-2 and B-12 etc.. For certain chronic diseases like Diabetes 1, M.S. R.A. and Advanced Prostate cancer, all dairy should be avoided. But for healthy people, the objective evidence shows that quality cheese in moderation or in small amounts from time to time can both favorably diversify the microbiota and boost longevity and anti-cancer pathways. Just like Flemming’s penecilin molds zap deleterious bacteria, recent published findings have confirmed key molecules in certain moldy cheese that can zap cancer cells. Raw organic A2 traditionally made cheese that does not lead to animal cruelty would be the type of cheese to use. Vegan rennet would be even better.

Holistic Solutions to Low Stomach Acid (Source)

Holistic Solutions to  Slow Bowel Movement and constipation (Source)

Euchanisea & Cancer See ACRI's Report

Euchanisea & Cancer
See ACRI’s Report

Session O: Dietary Supplementation & Optimal Longevity

“It’s not because we are old that we don’t play, it’s because we don’t play that we get old” (George Bernard Shaw)

Are supplements really needed to optimize Longevity ? (Source)

Case Study A:  Popular Supplementation for Healthy & Optimal  Lifespans (Source)

Case Study B: Unsafe and-or inefficient Supplementation (Source)

Case study C: Examples of Dietary Supplements ending up as expensive urine (Source)

Case study D: A Published Study Claims a 20 percent increase of Liver Damage coming from Dietary Supplements (Source)

Case Study E: Resveratrol in a  capsule, food or bottle ? Depends if one is a mouse, a patient, holistically inclined or a marketing agent (Source)

Case Study F: Analysis on Vitamin C, the big Electron Donor: Can there be  disease-based exceptions with lyposomal Vitamin C, IV Vitamin C, ascorbate palmitate and sodium ascorbate  ? (Source)

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Session O: Chronic Stress, Accelerated Aging & The Inner Saboteur

“Here we provide evidence that psychological stress— both perceived stress and chronicity of stress—is significantly associated with higher oxidative stress, lower telomerase activity, and shorter telomere length, which are known determinants of cell senescence and longevity, in peripheral blood mononuclear cells from healthy premenopausal women. Women with the highest levels of perceived stress have telomeres shorter on average by the equivalent of at least one decade of additional aging compared to low stress women”. (Source)

 Consciousness Disorders (Source)

Case Study: Successfully resolving the Self-Sabotage Disorder (Source)

 Hands-on Techniques to enhance Longevity and de-activate the Inner Saboteur (Source)

Workshop on Hormonal and neurotransmitter boosting and balancing as tools to develop more "joie de vivre" (enjoyment of Life). Click picture for details.

Top: red hot peppers, a great way to boost endorphins, immune function and metabolic pathways

Session P: Auto-immunity and Infections

“There is no fear in love: but perfect love casteth out fear”. (1 John 4: 18)

Analysis: Antibody tests, auto-immunity phenotypes and myriad infections, from Lyme disease to hepatitis, Epstein Barr, MRSA, the useful Measels, the less useful HPV and more. (Source)

Can holistic immunotherapy solve most auto-immune and infcetion challenges ? (Source)

Evidence that pineapples enzymes are clinically superior to the classic chemo 5-FU

Evidence that pineapples enzymes are clinically superior to chemo 5-FU

Session Q: Advanced Cancer Protocols

 Optimizing the Cancer Control, Repair & Reversal Code: a precondition to Optimal Longevity

« …si j’avais un cancer, je n’irai jamais dans un centre anticancéreux classique. Seules les victimes du cancer qui vivent loin de ces centres ont une chance. » “If i had a cancer, i would never to to a conventional anti cancer center. Only cancer victims who live far from these centers have a chance”. (Source) Pr Georges Mathé (famous contemporary French oncologist

 Integrative Versus Conventional Oncology Models: Strengths and Limitations (Source)

 Cancer Control and Reversal with Holistic Oncology: the ACR Institute’s HIP protocol (Source)

Cancer and Senescent Cells: An evolutionary marriage (Source)

Case Study A: Modified Citrus Pectin, Inflammation and Cancer. (Source)

To see other topics that this section covers, please click here. 

Cancer microenvironment

Cancer microenvironment is Key

Session R: Thermal Medicine: A French Speciality that would be of Benefit for the US Health-Care system

“Primum non nocere” (First do no Harm) Hippocrates, the Father of medicine

Case Study A: Heat Shock Proteins and  Hormesis Mechanism (Source)

Case Study B: Hyperthermia and immunotherapy (Source)

Sweet Potatoe Protein effective against Metastatic Cancer

Sweet Potatoe Protein can be effective against Metastatic Cancer and Hormonal disorders

Session S:  Optimizing balanced  Hormones & Neuro-transmitters & Regulating Cytokines

“Scientists said they were struck by how suddenly and overwhelmingly the 1918 flu struck seven macaques that were tested (…) The virus spread faster than a normal flu bug and triggered a “storm” response in the animal’s immune systems. Their bodies’ defenses went haywire, not knowing when to stop, researchers said. The lungs became inflamed and filled with blood and other fluids.  (…) “There was some surprise that it was that nasty,” University of Washington virologist and study co-author Michael Katze said. “It was the robustness of the immune system that helped victimize them.” (Source)

The Hormone Chemistry & Longevity (Source)

Sweet Potatoes and Yams to Balance Hormones: the Evidence (Source)

 Case Study A on DHEA, Pregenolone, Testosterone, Progesterone and Estrogen (Source)

Case Study B on Human Growth Hormone (HGH), IGF-1  Melatonin, Cortisol & Thyroxine (Source)

Case Study C on The Vasopressin & Oxytocin (Source)

The Oxytocin-Vasopressin Pathway in the Context of Love and Fear (Source)

Case Study: The Klotho Hormone as well as a few others (Source)

Neuropeptides, Neuro-transmitters & Healthy Longevity (Source)


Defining Excitatory and inhibitory processes in Neuro-transmitters (Source)

Case Study on Serotoin, Dopamine, Acetylcholine, Norepinpehrine and GABA (Source)

Neurotransmitters’ Imbalance (Source)

Cytokines Signaling Molecules, Cytokines-Storms, Inflammaging & the Body’s integrity (Source)

The Role of endogenous cytokines in premature death, disease, health and longevity (Source)

Case Study A: Homeostatic Imbalance  and Cytokine-storms (Source)

Case Study B: Holistic Interventions (Source)

Case Study C: Sepsis & Holistic Resolution (Source)

Case Study D: Influenza Pandemics (Source)

Dna-Telomere hallmark

Session S (bis):  Activating & Tweaking Key Longevity Genes

“Therefore I should infer from analogy that probably all the organic beings which have ever lived on this earth have descended from some one primordial form, into which life was first breathed.” (Darwin, Charles. On the Origin of Species. London: John Murray, Albermarle Street. 1859. pp. 484, 490).

What are Longevity Genes and what are their mechanisms of action ? (Source)

Case Study A: SNPs, Methylation & other Pathways (Source)

Case Study B: FOXO3 Activators and Rejuvenation (Source)

Case Study C: Other Longevity Genes, the Continuum of Ancestral Genes & the universal nature of biochemistry (Source)


Session T: Mitochondrial Bio-Genesis’ Restoration.

Mitochondrial bio-genesis and its mechanisms of action (Source)

Case Study A: Pyrroloquinoline quinone (PQQ) and Mitochondrial Biogenesis (Source)

Case Study B: Other Mitochondrial enhancers (Source)

Cancer microenvironment

Session U: Stem Cells: Repair, Replacement & Regeneration

“I regard consciousness as fundamental. I regard matter as derivative from consciousness”  Max Planck (leading expert in quantic physics, Nobel laureate)

Stem cells and their mechanisms of action (Source)

Case Study A: General Stem Cell Longevity boosters (Source)

Case Study B:  Stem Cells, Natural Beauty and Longevity (Source)


Session V: Telomerase Therapy

Telomere Biology and Mechanisms of Action (Source)

Telomere Shortening tends to accelerate Aging (Source)

Case Study: Telomerase Activators for Longevity (Source)

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Top: Rosemary, one of the Mediterranean plants that is abundant in both the Mediterranean longevity valleys and in centenarians’ guts

Session W: Cellular Senescence, Autophagy Regulation & Amyloidosis

“In humans and other animals, cellular senescence has been observed to be connected to the shortening of telomeres with each cell cycle; when telomeres become too short, the cells die. The length of telomeres is therefore the “molecular clock”, Harvard Professor Hayflick.

Cellular senescence, autophagy and their mechanisms of action (Source)

Case Study A:  A Review of different synolitics (senescent cell removers) (Source)

Case Study B: A review of different autophagy inducers and the link to longevity activation (Source)

Case Study C: Spermidine and Autophagy (Source)

  Case Study D: Amyloidosis and the Art of Removing extracellular Deposition of Misfolding Proteins (Source)

Case Study E: The Transthyretin transport protein (TTR) (Source)


Session X: Circadian Rythms Activation & DNA Repair

Circadian Rhythms and Mechanisms of Action (Source)

DNA Repair and Mechanisms of Action (Source) 

Case Study A: Nicotinamide Adenine Dinucleotide, NMN & DNA Repair (Source)

Case Study B: The metabolite NAD+ and DNA Repair (Source) 

Case Study C: Nicotinamide Riboside  (Source)

Case Study D:  Pterostilbene and Resveratrol Combo (Source)


Session Y: Monitoring Tests: From Self-testing to Genetic, Gut, Telomere & Methylation Evaluation

Which Monitoring tests are the best for longevity achievment and the reduction of chronic and degenerative diseases ?  (Source)

Evidence that Frankensen essential oil has anti-inflammatory and pro apoptotic properties against cancer.

Evidence that Frankensen essential oil has anti-inflammatory and pro apoptotic properties against cancer.

Session Z: Update on Today’s Bio-Engineering of anti-aging pharmaceuticals & Hi-Tech procedures

 Analysis of a few of the pending Longevity Human Clinical Trials (Source)

Case Study A: Targeting Senescent Cells with  Conventional Pharmaceuticals: successes and limitations (Source)

Case Study B:  The Safety and Efficiency of High Tech Procedures like Blood Plasma Transfer (young blood to older blood) (Source).

Case Study C: Longevity Peptides (Source)


Session : Summary

My people are destroyed from lack of knowledge” (Hosea 4:6).

 Honing in on Key Rejuvenation and Life Extension Techniques (Source)

 The Optimal Longevity Tune-up Protocol in a Nutshell (Source)

Case Study A: The Healing Milieu & the Entourage Effect (Source)

Case Study B: The Holistic Therapeutic Effect Principle (Source)


For the O.L Master Class’ Closing Remarks (from the Institute’s Book), click here. Reserved for the Registered Viewers


The expected Benefits from attending this Certification Master Class on Optimal Longevity and Cancer Reversal

“Man surprised me most about humanity. Because he sacrifices his health in order to make money. Then he sacrifices money to recuperate his health. And then he is so anxious about the future that he does not enjoy the present; the result being that he does not live in the present or the future; he lives as if he is never going to die, and then dies having never really lived.” The Dalai Lama

With this above-mentioned holistic knowledge, everyone who is motivated and compliant with the Institute’s holistic savoir-faire program and most of these evidence-based longevity techniques should be able to reach the supercentenarian status without major chronic diseases, that means to say 110 years and beyond of a healthy lifepan.

However, for those who have gotten into serious debilitating accidents, including surgical, radiological, cytotoxic chemo, genotoxic drug and other toxemia and stress incidents,  weaker genetic links and SNPs will emerge, among other deleterious biochemical happenings, thus making it more difficult to achieve this evolutionarily-based birth-right.

In particular, the knowledge imparted in this Master Class, if applied, can favorably impact the 18 longevity biomarkers we have examined, this means to say that the workshopee’s blood pressure, sugar stability, oxygen intake, neurogenesis, immune-regulation, hormonal signaling, insulin sensitivity, neurotransmitter firing, cholesterol-lipid profile, oral health, heart rate variability, hypothalamus-pituitary-adrenal axis homeostasis, mitochondrial function, microbiota diversity, bowel movement, deep sleep patterns, inflammation control (measured by CRP, interleukin 6, TNF alpha, inter alia) and many other health and longevity biomarkers should significantly improve within one to three months if not earlier.

As a double bonus, the workshopee, if holistically compliant and enthusiastically motivated, will strengthen his-her bio-terrain to such an extent that she-he will be quasi-immune from contracting some of the more common chronic “civilization” diseases, in particular, the Big Five, considered to be today’s “Black Plagues”: diabetes, cardiovascular events, cancer, auto-immunity and mental disorders like Azheimers, Depression and Parkinson.

And as a last double bonus, the workshopee should appear biologically younger with visible radiance and save money by getting rid of most or all of his-her “symptom” based prescription drugs, in conformity with Dr. William Osler’s recommendation (See his quote below)  and the exigencies of  Reason.

The supercentenarian birth-right status starts at 110 years, but our human biological potential, as of this writing, has been formally determined to be around 120 years (called the Hayflick limit), the epitome of which is represented by a French Mediterranean upbeat lady Jeanne Calment who died at 122 and a half after experiencing a Life of purpose, enjoyment and holistic savor-faire, including via 2.2 kilos of dark chocolate each week, lots of dancing, fencing, socializing, musicotherapy, red wine and relishing in the Mediterranean Lifestyle with her daily unflappability vibe.

However, more and more research indicates that some time in the not too distant future, we may be able to tweak our genetic material, longevity pathways and wellbeing genes to prolong a healthy lifespan to beyond 140 years.

But we are not there yet. We should therefore focus on what we know is achievable, a Lifespan of 120 years in relatively good shape, with all of one’s conscious awareness and major bodily functions working enough to experience Life to its fullest, with what we call in France, “La Joie de Vivre”.

Pr. Joubert (ACR & HM Institutes Director)

Exhibit A

Video Excerpt on a 2016  Optimal Longevity Medicine Lecture from Professor Joubert (Optimal Longevity Institute)

Exhibits B

Video extract on Longevity Genes by Professor Sinclair (Harvard University)

Exhibit C

Video excerpts on the Telomerase Enzyme’s ability to slow down and reverse the Aging Clock

“Health is a state of complete physical, mental and social well-being and not merely the absence of disease or infirmity.The enjoyment of the highest attainable standard of health is one of the fundamental rights of every human being without distinction of race, religion, political belief, economic or social condition”.   (World Health Organization’s Constitution)

Workshop on psycho-neuro-endocrinology and hormonal balancing Workshop

Master Class Presenter

Pr. Joubert: Biogerontologist  and holistic oncology expert from France. Former Professor of Law and Holistic Medicine.  (Bio) 

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Top:  Professor Joubert,  at the international integrative oncology convention (2016) in  San Diego toasting and “dégusting” (sipping) a small amount of red resveratrol-rich pinot wine with the conference President, Annie Brandt and her two assistants. “Wine is an appropriate article for mankind, both for the healthy body and for the ailing man.” Hippocrates 

Professor Joubert has also been a French certified ECOCERT organic agricultural peasant-farmer and Holistic Mediterranean Diet Chef & wine master. In this capacity, for this Master Class, he will teach how to prepare Med-Diet Longevity dishes and demonstrate how to pair wine with food as well as how to sip wine in a way that will enhance both wellbeing and neurogenesis. The claim that wine sipping can enhance neurogenesis is established by a preponderance of the published peer-reviewed evidence which will be shared during the Training.

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“Medicine is a collection of uncertain prescriptions, the results of which taken collectively, are more fatal than useful to mankind. Water, air and cleanliness are the chief articles in my pharmacopeia”. Napoleon Bonaparte  To which Ben  Franklin, the Spiritual Father of the U.S. of A replied:  “The best of all medicines is resting and fasting”. Thus, these two giants agree on therapeutic siestas….(napping). Today, one of the central public issues is  to incorporate this piece of advise within the legally enforceable health Code. Which would mean that all employers, including the Govenment and its military, FDA and judicial branches, would need to install meditation and siesta equipment and allow a good two hours  for lunch breaks. 

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To enroll in this Six Months Training, Pre-registration is required

For Info and Registration, please contact

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For those interested in Holistic Retreat Updates & Continuing Education & Workshops as well as the Institute’s Coaching & Training Sessions, click here.

To view the Institute’s Private coaching Secrets on Cancer cells’ Biological Strengths and Weaknesses Click Here (Password protected)

Students  will be able to access many key  videos that will teach them key biological processes and newly discovered pathways that spur cancer cells to be who they are,  and how we can holistically out-wit their formidable conquest “totalitarian” strategies.  As a result, coached patients will be more motivated to go  holistic in the direction of greater cancer control and malignancy reversal. And as a bonus, their healthy lifespan may significantly increase.

“Man surprised me most about humanity. Because he sacrifices his health in order to make money. Then he sacrifices money to recuperate his health. And then he is so anxious about the future that he does not enjoy the present; the result being that he does not live in the present or the future; he lives as if he is never going to die, and then dies having never really lived.” The Dalai Lama 
Screen Shot 2017-09-18 at 4.41.30 PM
“The young physician starts life with 20 drugs for each disease, and the old physician ends life with one drug for 20 diseases.”  (William Osler)  William Osler was a highly respected physician, professor and writer who authored “The Principles and Practice of Medicine” in 1892, which served as the standard clinical medicine text for 40 years. Later on in his life he wrote that one of the most crippling teachings in Medical schools is this “one pill for an ill” principle.


“The art of medicine consists in amusing the patient while Nature cures the disease.”  Voltaire. One of 18th century Voltaire’s lessons to heal and be happy is to “cultivate one’s garden” (cf in his book Condide), that which can be translated to mean the cultivation of the low-key attitude of being joyfully humble and humbly joyful with an uplifting sense of purpose, awe and gratitude holistically expressed in the “now and here”, what is  called “la joie de vivre”. 
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Evidence that Nigella Sativa is clinically superior to many cancer drugs. To VIEW the Slide Show's ARTICLES & VIDEOS, consider CLICK-ing directly on the Screen.

DISCLAIMER. Nothing in this blog-website should be construed as medical or legal advise, including, but not limited to replies, comments and posts, all of which should not be deemed to constitute either a therapist-patient nor an attorney-client relationship. For all and any serious disease, the Institute recommends consulting with a competent Health-care practitioner who has both conventional and holistic medical training and clinical experience.
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